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  1. Products
  2. Endotoxin Removal Column NEA-1000R

Endotoxin Removal Column NEA-1000R

NAGASE offers a comprehensive suite of solutions for overcoming endotoxin challenges in biomaterials. Our services and products utilize proprietary High-Capacity Cellulose Carriers and optimized ligand designs to achieve superior adsorption performance compared to conventional technologies.

 

NEA-1000R Column: A ready-to-use endotoxin removal column designed for research and testing, capable of selectively removing endotoxins from diverse proteins and polysaccharides.

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Chemical Name:

Endotoxin Removal Column

Applications & Uses:

  • Implantable Medical Devices: Refining raw materials to meet stringent biological safety standards.
  • Regenerative Medicine: Ensuring ultra-low endotoxin environments for sensitive cell-based therapies.
  • Biopharmaceutical Research: Selectively removing endotoxins from proteins (e.g., BSA, Gamma globulin) and polysaccharides (e.g., Pullulan) with high recovery rates.
  • Cell Culture Substrates: Preparing high-purity base materials for research applications.
FAQ

Benefits:

  • High Adsorption Capacity: Our technology offers adsorption capacities several times higher than conventional methods, reaching up to 1.0 × 10^7 EU/ column.
  • Superior Selectivity: Efficiently targets endotoxins even in challenging acidic solutions or viscous formulations without clogging.
  • Gentle Processing: Avoids harsh conditions (heat, strong acids, or alkalis) that can degrade sensitive product integrity.
  • High Recovery Rates: Maintains excellent protein and polysaccharide recovery (often between 96% to 99%) after treatment.
  • Simplicity: NEA-1000R columns are easy to operate and come individually packed in sterile packages.

Performance Attributes:

NEA-1000R SpecificationsPackaging: 1mL column x 5.*Sterilization: EOG Sterilized.*Storage: Refrigeration required.Endotoxin removal from proteins
Samplelsoelectric
point
Before
treatment
After
treatment
Endotoxin
removal rate
Protein
recovery rate
BSA4.930EU/ml0.1EU/ml≥99%98%
Gamma globulin7.441EU/ml0.5EU/ml≥99%99%
Cytochrome C10.627EU/ml0.1EU/ml≥99%96%
Test conditions : protein solution (500μg/ml, 0.02M phosphate buffer, pH7.0, ionic strengthμ= 0.2), LPS(EcoliUKT-B), flow rate 0.1mL/min

Approvals & Certifications:

ISO9001

Manufacturer:

Nagase ChemteX Corporation

Industries:

  • Healthcare & Pharmaceuticals

Categories:

  • Gelling Agents
  • Low Endotoxin

Country of origin:

  • JP

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© {{lastPublishedYear}} Nagase & Co., Ltd. All rights reserved.