We are developing fermentation technologies to use Streptomyces strains as host cells for producing chemicals and ingredients.

Nagase Bio-Innovation Center
Our Nagase Bio-Innovation Center researches and evaluates opportunities to solve social and environmental issues. Through tireless research on microorganisms, enzymes, and enzymatic reactions, the Nagase Bio-Innovation Center delivers sustainable materials to help answer the world’s most pressing problems.
Unavailable Made Available & Sustainable
At NAGASE, we’re committed to working on projects that contribute to the health, safety, and prosperity of society and the environment. Our Nagase Bio-Innovation Center is focused on achieving breakthroughs in biochemical manufacturing using proprietary technologies.
Technologies that Transform our Future
Streptomyces
tRNA Availability
We have created a technology that uses high-availability transfer RNA (tRNA) to improve production yields in microbial fermentation.
OTR Simulator
For scale-up studies of aerobic cultures, we developed a simulator that can perform thorough and precise calculations of oxygen transfer rate (OTR).
Projects
Ergothioneine
We are using fermentation techniques to produce the natural antioxidant ergothioneine. A safe and stable compound, ergothioneine is transported to the brain and throughout the body.
Ferritin
We have developed a technology to mass-produce ferritin with proprietary recombinant DNA techniques.
D-Sedoheptulose
We’ve targeted the D-Sedoheptulose produced by Streptomyces and developed technology to mass-produce it using N-STePP™.
Research Achievements & Activities
Related Websites
Nagase Viita Co., Ltd.
Nagase ChemteX Corporation
Related Resources
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