Snake Venom Enzymes
A premier, globally recognized selection of highly purified native snake venom enzymes engineered specifically as diagnostic activators or reagents for blood coagulation testing, platelet aggregation assays, and hemostasis research. Purified through advanced affinity chromatography and fractional extraction, these enzymes selectively trigger or inhibit specific coagulation cascade pathways with absolute precision.
Applications & Uses:
- Heparin-insensitive fibrinogen determination and fibrinogen polymerization assays
- Direct activation of specific clotting factors (Factor X, Factor V, or Prothrombin)
- Screening and confirmation assays for Lupus Anticoagulants (LA)
- Activation and studies of human platelets via specific receptors
Benefits:
- Strict heparin insensitivity: Thrombin-like snake venom enzymes (such as Batroxobin) are unaffected by therapeutic heparin, ensuring accurate fibrinogen measurements
- Absolute pathway specificity: Specific activators (such as Protac for rapid protein C activation, or RVV-X for Factor X activation) target single clotting factors without broad proteolysis
- Exceptional batch reproducibility: Produced under rigorous standardized extraction and purification controls to eliminate lot-to-lot kinetics variation
- Zero detectable cross-contamination: Advanced chromatographic isolation ensures no unwanted active side-components or trace infectious pathogens
Performance Attributes:
- Exhibit rapid, highly reproducible clotting and activation kinetics.
- Activity is strictly standardized and calibrated matching international standards.
- Demonstrate excellent long-term stability in both lyophilized and liquid bulk formats under refrigerated conditions.
Sub Category:
EnzymesPhysical Properties:
| Appearance: | White to off-white lyophilized solid, or clear liquid |
|---|---|
| Solubility: | Highly soluble in physiological saline or standard aqueous buffers |
Chemical Properties:
| Purity: | Equal to or greater than 95% by SDS-PAGE |
|---|---|
| Form: | Lyophilized powder vacuum-sealed or stable buffered liquid format |
| Viral safety: | Free of detectable host-derived pathogens |
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