Elastase-1 is a proteolytic enzyme produced specifically by the pancreas. Elevated levels in blood indicate pancreatic inflammation or cancer.
Frequently Asked Questions
It is quantified by latex-enhanced immunoturbidimetry, where the enzyme reacts with anti-human Elastase-1 antibodies to form measurable aggregates.
Elastase-1 levels rise early in pancreatic cancer, making it useful for early detection compared to other markers like amylase, CEA, or CA19-9.
Pancreatic cancer, pancreatitis, and pancreatic duct obstruction all lead to elevated Elastase-1 concentrations in serum and plasma.
The reagent offers high reproducibility (C.V. <1%), a broad dynamic range up to 4,000 ng/dL, and stable shelf life up to 12 months at 2–10 °C.