Rheumatoid Factor (RF)
A highly specific, clinical-grade latex immunoturbidimetric assay reagent designed for the quantitative determination of Rheumatoid Factor (RF) in human serum or plasma on automated biochemical analyzers. Utilizing polystyrene latex particles sensitized with highly purified heat-denatured human IgG, this reagent selectively binds rheumatoid factors (primarily IgM autoantibodies) with minimal cross-reactivity and outstanding lot-to-lot consistency.
Applications & Uses:
- Quantitative determination of Rheumatoid Factor (RF) in human serum and plasma
- Screening and clinical diagnosis of rheumatoid arthritis (RA)
- Routine biochemistry screening and autoimmune disease diagnostics on automated analytical systems
Diagnostic Target Panels:
- Autoimmune screening: Rheumatoid Arthritis (RA) diagnostics
- Routine clinical chemistry panels
Benefits:
- Highly specific heat-denatured human IgG sensitisation: Uses pure denatured human IgG to ensure exclusive binding to rheumatoid factors, eliminating non-specific interferences.
- Excellent precision and reproducibility: Demonstrates outstanding within-run and between-run accuracy with low coefficient of variation (CV) for consistent diagnostics.
- High clinical correlation: Proven high correlation against conventional reference assays and reference standards, ensuring seamless platform transition.
- Minimized hook effect: Features a robust formulation that avoids false negatives at standard clinical high-concentration ranges.
Performance Attributes:
- Displays exceptional analytical sensitivity and wide reportable range.
- Highly resistant to endogenous interference from lipids, bilirubin, and hemolysis.
- Liquid ready-to-use format supports maximum high-throughput workflow efficiency.
Sub Category:
OEM Bulk ReagentsChemical Properties:
| Purity: | Free of residual free antibodies or uncoupled IgG |
|---|---|
| Host of antibodies: | Highly purified human IgG source |
| Buffer: | Supplied in physiological buffered saline |
| Viral Safety: | Free of organic solvents |
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