HbA1c is a glycated form of hemoglobin that reflects average blood glucose levels over the past 2–3 months. It is used as a reliable indicator of long-term glucose control in diabetes management.
HbA1c Latex Agglutination Reagents
A state-of-the-art, NGSP-standardized latex turbidimetric agglutination reagent system designed for the quantitative determination of glycated hemoglobin A1c (HbA1c) levels in human whole blood. Enabling direct HbA1c measurement from a single dose-response curve without requiring prior centrifugation.
Applications & Uses:
HbA1c measurement is essential for long-term glucose control and diabetes diagnostics.
- Monitoring of chronic diabetes in clinical settings
- Diagnosis of type 1 and type 2 diabetes based on long-term glycemic control
- Routine testing in health check-ups and preventive care
- Evaluation of therapy effectiveness for insulin or oral hypoglycemics
- Research studies on metabolic diseases and lifestyle disorders
Benefits:
Our HbA1c assay uses latex turbidimetry to deliver precise, standardized results across laboratories.
- Assay principle: Based on latex turbidimetric agglutination for high sensitivity and speed
- Standardized range: Measuring range from 3.3% to 14.5% (NGSP)
- High correlation: Coefficient of 0.99 compared to commercial HPLC methods
- NGSP-aligned normal values: Reference range of 4.6% to 6.2%
- OEM supply: Available in bulk for integration into IVD platforms
Additional Information
Latex Immunoagglutination Assay
This test provides a convenient, quantitative assay for measuring concentrations of hemoglobin A1c (HbA1c) in blood. The level of HbA1c is a useful index in controlling blood glucose levels in patients with diabetes. This test is based on latex immunoagglutination where HbA1c in the test sample is absorbed onto latex particles, then cross-linked anti-HbA1c is added to form an antigen-antibody reaction. Finally the percentage of HbA1c is obtained from the dose response curve.
Performance Attributes:
- Wide NGSP-standardized analytical range covering 3.3% to 14.5% HbA1c.
- NGSP-aligned normal reference range set at 4.6% to 6.2%.
- Reaction principle: HbA1c in the blood specimen is adsorbed onto monodisperse latex particles, and cross-linked anti-HbA1c monoclonal antibody is added to induce turbidimetric agglutination.
Sub Category:
OEM Bulk ReagentsPhysical Properties:
| Appearance: | Milky white latex suspension (Reagent 1) and clear antibody solution (Reagent 2). |
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Chemical Properties:
| Active components: | Polystyrene latex beads formulated to absorb whole blood HbA1c, paired with a highly specific mouse monoclonal anti-human HbA1c cross-linking antibody. Fully stabilized buffer matrix. |
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Frequently Asked Questions
NAGASE offers a latex agglutination assay for HbA1c quantification, delivering rapid and reproducible results with strong correlation to HPLC-based reference methods.
According to NGSP standards, normal values lie between 4.6% and 6.2%, while diabetic patients typically show elevated levels.
The assay offers a wide measuring range (3.3–14.5%), fast results, and compatibility with automated analyzers, making it ideal for high-throughput clinical use.
Yes, NAGASE provides the HbA1c assay in bulk quantities, ready for integration into OEM diagnostic systems worldwide.
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