Magnetic Beads
A highly standardized portfolio of high-purity superparamagnetic nanobeads and magnetic nanoparticles (MNPs) engineered specifically for nucleic acid extraction, protein purification, and high-performance in vitro diagnostic (IVD) assays. Utilizing a unique technology where the particle core itself is composed of active magnetic iron oxide (magnetite, Fe3O4), these beads provide exceptionally fast magnetic response times and outstanding redispersion kinetics. Available in precise nanometer sizes (10 nm, 100 nm, 300 nm) and diverse chemical surface modifications.
Applications & Uses:
- High-efficiency nucleic acid (DNA/RNA) extraction and molecular testing on automated platforms (specifically silica-coated series)
- Protein purification, biomarker isolation, and Western blotting assays (specifically ligand-conjugated series)
- Microplate sandwich ELISA, biochemical assays, and chemiluminescent immunoassay (CLIA) systems
- Raw materials for composite microsphere manufacturing and magnetic functionalization of polymer beads (specifically MNP series)
Diagnostic Target Panels:
- Molecular diagnostics and pathogen PCR detection kits
- Autoimmune disease testing and protein diagnostics panels
- Extrinsic/intrinsic bio-separation and cellular diagnostics
Benefits:
- Rapid Magnetic Separation: Magnetic core structure enables quick magnetic response and efficient separation.
- Versatile Particle Size Options: Offers various particle size options to optimize matching with different extraction kits and reagent formulations.
- Excellent Redispersion Capability: Superparamagnetic properties prevent residual magnetism, allowing immediate redispersion without aggregation after magnetic field removal.
- Diverse Surface Modifications: Supports a wide range of functional groups and surface chemistries for covalent coupling or specific ligand binding.
- High Magnetic Capture Efficiency: High saturation magnetization ensures reliable capture performance and efficient recovery of target substances.
Performance Attributes:
- Demonstrate rapid, highly reproducible magnetic separation kinetics within 2 to 20 seconds.
- Ensure robust ligand coupling efficiency with low non-specific background binding.
- Maintain stable colloidal dispersion state under recommended physiological buffered systems.
Sub Category:
BeadsPhysical Properties:
| Appearance: | Brown to black aqueous suspension |
|---|---|
| Available particle sizes: | 10 nm, 100 nm, 300 nm |
| Specific Gravity: | Approximately 1.15 to 1.35 |
| Particle content: | Equal to or greater than 50.0 mg/mL (in physiological saline) |
Chemical Properties:
| Composition: | Magnetite (Fe3O4) magnetic core with nonmagnetic shells |
|---|---|
| Surface modifications: | Silica coating, Hydroxyl, Carboxyl, Amino, Thiol, Epoxy, Vinyl, or Avidin |
| Magnetic properties: | Superparamagnetic (zero remanence) |
| Saturation magnetization: | Approximately 63 emu/g (for 10 nm), approximately 70 emu/g (for 100 nm and 300 nm) |
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