Cephalin
A highly purified, clinical-grade rabbit brain cephalin (phospholipids) liquid extract designed extensively as a phospholipid source in phospholipid-dependent coagulation assays, specifically for activated partial thromboplastin time (aPTT) reagents. Extracted from cholesterol-free rabbit brain acetone powder using precise organic solvents, this product is formulated in physiological saline and frozen at -20 degrees C to provide an easy-to-use, highly stable, and reliable platelet-substitute activator.
Applications & Uses:
- Standard phospholipid source and platelet substitute in activated partial thromboplastin time (aPTT) diagnostic reagents
- Formulation of phospholipid-dependent assays measuring intrinsic pathway clotting factors (such as Factor VIII, IX, XI, or XII)
- Biochemical research on phospholipid-protein binding mechanisms and blood coagulation curves
Benefits:
- High Sensitivity & Reproducibility in aPTT Assays: Delivers precise and consistent aPTT reaction times for accurate coagulation testing.
- High Purity & Cholesterol-Free: Contains highly purified active phospholipids without cholesterol interference, supporting clear assay performance.
- Convenient Ready-to-Use Format: Supplied pre-suspended in saline solution, eliminating the need for complex reconstitution or dilution steps.
- High Biological Safety Standards: Derived from certified healthy animal tissues to ensure strict biosecurity and quality control.
Performance Attributes:
- Guarantees aPTT reaction times within 25.0 to 40.0 seconds in clinical calibration systems.
- Fully retains stable active colloid dispersion upon thawing, without natural sedimentation or coagulation.
- Chemically consistent phospholipid composition of 95% or more.
Approvals & Certifications:
Regulation (EU) 142/2011 Chapter 8 certified, suitable for clinical IVD manufactureSub Category:
Animal DerivedPhysical Properties:
| Appearance: | Frozen opaque solid (opaque yellowish liquid after thawing) |
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| Odor: | Odorless |
| Solubility: | Fully dispersible in physiological saline |
Chemical Properties:
| Active ingredient: | Chromatographically extracted rabbit brain phospholipids (primarily cephalin / phosphatidylethanolamine); Free of biological infectious pathogens. |
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