RESOURCES

All-in-One TIDES Approach for Next-Generation Therapeutics

July 29, 2026

Breaking the Purity and Recovery Trade-off

What if you no longer had to choose between purity and recovery?

Downstream processing remains one of the biggest bottlenecks in peptide and oligonucleotide (TIDES) manufacturing. Traditionally, achieving higher purity has meant sacrificing product recovery, increasing manufacturing costs and limiting productivity.
Advanced technologies such as twin-column continuous chromatography and mixer-type lyophilization are transforming downstream processing. However, equipment alone is not enough. Unlocking their full potential requires deep process expertise and intelligent integration across the entire manufacturing workflow.

In this white paper, discover how the process scientists and engineers at our trusted partner, PeptiStar, leveraged Integrated Process Control to overcome the traditional purity–recovery trade-off—delivering higher purity, higher recovery, and significantly shorter freeze-drying cycles.
Learn how our All-in-One TIDES approach can help optimize manufacturing performance through:
• Higher Purity
• Higher Recovery
• Shorter Cycle Times
• Lower Manufacturing Cost
• Greater Sustainability

Download the full white paper by completing the form below.

Downstream processing remains one of the biggest bottlenecks in peptide and oligonucleotide (TIDES) manufacturing. Traditionally, achieving higher purity has meant sacrificing product recovery, increasing manufacturing costs and limiting productivity.
Advanced technologies such as twin-column continuous chromatography and mixer-type lyophilization are transforming downstream processing. However, equipment alone is not enough. Unlocking their full potential requires deep process expertise and intelligent integration across the entire manufacturing workflow.
In this white paper, discover how the process scientists and engineers at our trusted partner, PeptiStar, leveraged Integrated Process Control to overcome the traditional purity–recovery trade-off—delivering higher purity, higher recovery, and significantly shorter freeze-drying cycles.
Learn how our All-in-One TIDES approach can help optimize manufacturing performance through:
• Higher Purity
• Higher Recovery
• Shorter Cycle Times
• Lower Manufacturing Cost
• Greater Sustainability

Download the full white paper by completing the form below.