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25 Nov 2000

Nagase developed Vegetable-DHA-containing Oil with its Fermentation Technology


Nagase and its affiliate Nagase Biochemical have co-developed Docohexaphen Acid (DHA) containing oil, which is a main material for glucose, using microorganism fermentation biotechnology. It is vegetable oil based compare to existing fish oil based DHA containing oil.

Besides containing more DHA, this oil also contains a large amount of (n-6) DPA, which does not disrupt aliphatic acid balance in a living body. It was all along believed that aliphatic acid balance becomes unstable when only DHA is taken.

This new vegetable DHA containing oil "DHA-NAGASE" is generated by the fungi cultured with vegetable originated glucose, which Nagase developed from the culture technology of Nagase Biochemical and others. It exhibits different aliphatic acid composition from general DHA oil with fish oil origin. In addition to high concentration of DHA, it contains about 10 % of (n-6) DPA in equal amount to highly unsaturated fatty acid.

It is commonly believed to be important to take appropriate amount of highly unsaturated fatty acid as essential fatty acid keeps one healthy. It was revealed in animal experiments that only single dosage of DHA will increase DHA level in a living body, else it will decrease arachidonic acid, which is essential to living thing and will lead to the imbalance of n-3 system and n-6 system.

The administration of DHA-NAGASE evidently shows no decrease in amount of Arachidonic Acid even as DHA increases and aliphatic acid balance in living body is being maintained. The new product proves possible not just the replenishment of DHA but that it is possible also to produce the kind of health food that does not intervene with aliphatic acid balance.

In addition to the stable aliphatic acid composition, the product is semi solid at room temperature hence it is easily applicable to a solid product. Other advantage is that it has more of DHA and (n-6) DPA and less of ARA and EPA. A big plus point is that there is almost no smell of fish.

Nagase has a plan to scale up commercialization through sample offering and some customer has already begun sampling of the product. A business plan for the product has been elaborately drawn out and it is set in a direction that Nagase Biochemical will manufacture the new product while Nagase will sell and distribute it.

(Source: Nagase & Co. Ltd)

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